Sisley is redefining the way we think about aging with the launch of Sisleÿa L’Intégral Anti-Âge Longevity Essential Serum, a high-performance treatment created to help skin maintain its vitality for as long as possible.
Drawing on cutting-edge longevity research, this serum reconnects three essential systems that keep skin youthful – the cutaneous system, the vascular system, and the immune system – so that skin can regenerate, glow, and defend itself against visible signs of aging.
Where Science Meets Skin Care

This next-generation formula combines a biotechnological fraction of β-glucans that stimulates regeneration messengers, a new Gingko extract that reactivates the natural elimination of senescent fibroblasts, and a duo of plant-based actives that restore skin’s density and resilience.
Red Vine extract revives skin radiance, while two types of hyaluronic acid provide deep and lasting hydration in a silky, serum-in-oil texture that absorbs beautifully and leaves skin plump and comfortable.
Proven Results

Clinical tests showed impressive improvements. After one month of use twice a day, most women reported that wrinkles were less visible and their skin looked smoother and more radiant. After two months, instrumental tests revealed an increase in dermal density and a more even, luminous complexion with a noticeable reduction in redness.

The Sisleÿa Longevity Essential Serum is available now at all Sisley Paris counters and online at Sisley-Paris.com.








